Preheat oven to 350°F (175°C).
Mix ingredients: In a large bowl, combine ground beef, bread crumbs, egg, ketchup, garlic powder, salt, and black pepper. Mix gently until just combined; overmixing can make the meatloaf dense.
Shape the loaf: Transfer the mixture to a greased or parchment-lined baking sheet. Shape it into a loaf or place it into a greased loaf pan.
Add topping: Spread a thin layer of ketchup over the top of the meatloaf for extra flavor and moisture.
Bake: Place the meatloaf in the oven and bake for about 45 minutes.
Rest and serve: Let the meatloaf rest for 5-10 minutes before slicing.
